Great Lakes Regional Center of Excellence

Great Lakes Regional Center of Excellence

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2010 GLRCE Publications

Past years

2010 |2009 | 2008 | 2007 | 2006 | 2005 | 2004 | 2003

Strandberg KL, Rotschafer JH, Vetter SM, Buonpane RA, Kranz DM, Schlievert PM. 2010. Staphylococcal superantigens cause lethal pulmonary disease in rabbits. J. Infect. Dis. 202:1690-7. PMC2974057
Full text at Pubmed Central

Heaton NS, Randall G. 2010. Dengue virus-induced autophagy regulates lipid metabolism. Cell Host Microbe 8:422-32. PMC3026642
Full text at Pubmed Central

Heaton NS, Perera R, Berger KL, Khadka S, Lacount DJ, Kuhn RJ, Randall G. 2010. Dengue virus nonstructural protein 3 redistributes fatty acid synthase to sites of viral replication and increases cellular fatty acid synthesis. Proc. Natl. Acad. Sci. U.S.A. 107:17345-50. PMC2951450
Pubmed Abstract 

Kennedy AD, Bubeck Wardenburg J, Gardner DJ, Long D, Whitney AR, Braughton KR, Schneewind O, Deleo FR. 2010. Targeting of Alpha-Hemolysin by Active or Passive Immunization Decreases Severity of USA300 Skin Infection in a Mouse Model. J. Infect. Dis. 202:1050-8. PMC2945289
Pubmed Abstract 

Frankel MB, Wojcik BM, DeDent AC, Missiakas DM, Schneewind O. 2010. ABI domain-containing proteins contribute to surface protein display and cell division in Staphylococcus aureus. Mol. Microbiol. 78:238-52. PMC Journal - In Process
Full text at Pubmed Central

Nanbo A, Imai M, Watanabe S, Noda T, Takahashi K, Neumann G, Halfmann P, Kawaoka Y. 2010. Ebolavirus is internalized into host cells via macropinocytosis in a viral glycoprotein-dependent manner. PLoS Pathog. 6:.. PMC2944813
Full text at Pubmed Central

Wang N, Mattis DM, Sundberg EJ, Schlievert PM, Kranz DM. 2010. A Single, Engineered Protein Therapeutic Neutralizes Exotoxins from Both Staphylococcus and Streptococcus. CVI 17:1781-9. PMC2976085
Full text at Pubmed Central

Kern J, Ryan C, Faull K, Schneewind O. 2010. Bacillus anthracis surface-layer proteins assemble by binding to the secondary cell wall polysaccharide in a manner that requires csaB and tagO. J. Mol. Biol. 401:757-75. PMCID pending
Pubmed Abstract 

Wilson DJ, Aldrich CC. 2010. A continuous kinetic assay for adenylation enzyme activity and inhibition. Anal. Biochem. 404:56-63. PMC2900519
Pubmed Abstract 

Kim HK, DeDent A, Cheng AG, McAdow M, Bagnoli F, Missiakas DM, Schneewind O. 2010. IsdA and IsdB antibodies protect mice against Staphylococcus aureus abscess formation and lethal challenge. Vaccine 28:6382-92. PMC3095377
Full text at Pubmed Central

Kim HK, Cheng AG, Kim HY, Missiakas DM, Schneewind O. 2010. Nontoxigenic protein A vaccine for methicillin-resistant Staphylococcus aureus infections in mice. J. Exp. Med. 207:1863-70. 0
Full text at Pubmed Central

Karalewitz AP, Kroken AR, Fu Z, Baldwin MR, Kim JJ, Barbieri JT. 2010. Identification of a Unique Ganglioside Binding Loop within Botulinum Neurotoxins C and D-SA . Biochemistry 49:8117-26. PMC2939319
Full text at Pubmed Central

Huseby MJ, Kruse AC, Digre J, Kohler PL, Vocke JA, Mann EE, Bayles KW, Bohach GA, Schlievert PM, Ohlendorf DH, Earhart CA. 2010. Beta toxin catalyzes formation of nucleoprotein matrix in staphylococcal biofilms. Proc. Natl. Acad. Sci. U.S.A. 107:14407-12. PMC2922554
Pubmed Abstract 

Herrou J, Foreman R, Fiebig A, Crosson S. 2010. A structural model of anti-anti-sigma inhibition by a two-component receiver domain: the PhyR stress response regulator. Mol. Mic. 78:290-304. PMC2959141
Full text at Pubmed Central

Cheng AG, McAdow M, Kim HK, Bae T, Missiakas DM, Schneewind O. 2010. Contribution of coagulases towards Staphylococcus aureus disease and protective immunity. PLoS Pathog. 6:. PMC2916881
Full text at Pubmed Central

Wilke GA, Bubeck Wardenburg J. 2010. Role of a disintegrin and metalloprotease 10 in Staphylococcus aureus alpha-hemolysin-mediated cellular injury. Proc. Natl. Acad. Sci. U.S.A. 107:13473-8. PMC2922128
Pubmed Abstract 

Onunkwo CC, Hahn BL, Sohnle PG. 2010. Clearance of experimental cutaneous Staphylococcus aureus infections in mice. Arch. Dermatol. Res. 302:375-82. PMC2877165
Pubmed Abstract 

Jasenosky LD, Neumann G, Kawaoka Y. 2010. Minigenome-based reporter system suitable for high-throughput screening of compounds able to inhibit Ebolavirus replication and/or transcription. Antimicrob. Agents Chemother. 54:3007-10. PMC2897319
Full text at Pubmed Central

Schmitt J, Karalewitz A, Benefield DA, Mushrush DJ, Pruitt RN, Spiller BW, Barbieri JT, Lacy DB. 2010. Structural analysis of botulinum neurotoxin type G receptor binding . Biochemistry 49:5200-5. PMC2894633
Pubmed Abstract 

Raymond DD, Piper ME, Gerrard SR, Smith JL. 2010. Structure of the Rift Valley fever virus nucleocapsid protein reveals another architecture for RNA encapsidation. Proc. Natl. Acad. Sci. U.S.A. 107:11769-74. PMC2900692
Full text at Pubmed Central

Radhakrishnan GK, Splitter GA. 2010. Biochemical and functional analysis of TIR domain containing protein from Brucella melitensis. Biochem. Biophys. Res. Commun. 397:59-63. PMC2900483
Pubmed Abstract 

Katpally U, Voss NR, Cavazza T, Taube S, Rubin JR, Young VL, Stuckey J, Ward VK, Virgin HW, Wobus CE, Smith TJ. 2010. High-resolution cryo-electron microscopy structures of murine norovirus 1 and rabbit hemorrhagic disease virus reveal marked flexibility in the receptor binding domains. J. Virol. 84:5836-41. PMC2876586
Full text at Pubmed Central

Taube S, Rubin JR, Katpally U, Smith TJ, Kendall A, Stuckey JA, Wobus CE. 2010. High-resolution x-ray structure and functional analysis of the murine norovirus 1 capsid protein protruding domain. J. Virol. 84:5695-705. PMC2876589
Full text at Pubmed Central

Lan L, Cheng A, Dunman PM, Missiakas D, He C. 2010. Golden pigment production and virulence gene expression are affected by metabolisms in Staphylococcus aureus. J. Bacteriol. 192:3068-77. PMC2901709
Full text at Pubmed Central

Noda T, Hagiwara K, Sagara H, Kawaoka Y. 2010. Characterization of the Ebola virus nucleoprotein-RNA complex. J. Gen. Virol. 91:1478-83. PMC2878588
Full text at Pubmed Central

Mayhoub AS, Talukdar A, Cushman M. 2010. An oxidation of benzyl methyl ethers with nbs that selectively affords either aromatic aldehydes or aromatic methyl esters. J. Org. Chem. 75:3507-10. PMC2871065
Pubmed Abstract 

Peltier DC, Simms A, Farmer JR, Miller DJ. 2010. Human Neuronal Cells Possess Functional Cytoplasmic and TLR-Mediated Innate Immune Pathways Influenced by Phosphatidylinositol-3 Kinase Signaling. J. Immunol. 184:7010-21. PMC2887731
Pubmed Abstract 

Fiebig A, Castro Rojas CM, Siegal-Gaskins D, Crosson S. 2010. Interaction specificity, toxicity and regulation of a paralogous set of ParE/RelE-family toxin-antitoxin systems. Mol Microbiol 77:236–251. PMC2907451
Pubmed Abstract 

Zakharova E, Grandhi J, Wewers MD, Gavrilin MA. 2010. Mycoplasma suppression of THP-1 Cell TLR responses is corrected with antibiotics. PLoS ONE 5:e9900. PMC2845629
Pubmed Abstract 

Yamayoshi S, Neumann G, Kawaoka Y. 2010. Role of the GTPase Rab1b in ebolavirus particle formation. J. Virol. 84:4816-20. PMC2863720
Full text at Pubmed Central

Bell BL, Mohapatra NP, Gunn JS. 2010. Regulation of virulence gene transcripts by the Francisella novicida orphan response regulator PmrA: role of phosphorylation and evidence of MglA/SspA interaction. Infect. Immun. 78:2189-98. PMC2863534
Full text at Pubmed Central

Stenmark P, Dong M, Dupuy J, Chapman ER, Stevens RC. 2010. Crystal structure of the botulinum neurotoxin type G binding domain: insight into cell surface binding. J. Mol. Biol. 397:1287-97. PMC2928138
Pubmed Abstract 

Dong J, Thompson AA, Fan Y, Lou J, Conrad F, Ho M, Pires-Alves M, Wilson BA, Stevens RC, Marks JD. 2010. A single-domain llama antibody potently inhibits the enzymatic activity of botulinum neurotoxin by binding to the non-catalytic alpha-exosite binding region. J. Mol. Biol. 397:1106-18. PMC2903050
Pubmed Abstract 

Daniel A, Euler C, Collin M, Chahales P, Gorelick KJ, Fischetti VA. 2010. Synergism between a novel chimeric lysin and oxacillin protects against infection by methicillin-resistant Staphylococcus aureus. Antimicrob. Agents Chemother. 54:1603-12. PMC2849374
Pubmed Abstract 

Mohapatra NP, Soni S, Rajaram MV, Dang PM, Reilly TJ, El-Benna J, Clay CD, Schlesinger LS, Gunn JS. 2010. Francisella Acid Phosphatases Inactivate the NADPH Oxidase in Human Phagocytes. Journal of immunology (Baltimore, Md. : 1950) 184:5141-50. PMC2952287
Pubmed Abstract 

Dalton KM, Crosson S. 2010. A conserved mode of protein recognition and binding in a ParD-ParE toxin-antitoxin complex. Biochemistry 49:2205-15. PMC2846751
Pubmed Abstract 

Schiano CA, Bellows LE, Lathem WW. 2010. The small RNA chaperone Hfq is required for the virulence of Yersinia pseudotuberculosis. Infection and immunity 78:2034-44. PMC2863511
Full text at Pubmed Central

Riley SP, Goh KG, Hermanas TM, Cardwell MM, Chan YG, Martinez JJ. 2010. The Rickettsia conorii autotransporter protein Sca1 promotes adherence to non-phagocytic mammalian cells. Infection and immunity 78:1895-904. PMC2863548
Full text at Pubmed Central

Stowe GN, Silhár P, Hixon MS, Silvaggi NR, Allen KN, Moe ST, Jacobson AR, Barbieri JT, Janda KD. 2010. Chirality holds the key for potent inhibition of the botulinum neurotoxin serotype a protease. Org. Lett. 12:756-9. PMC2821465
Pubmed Abstract 

McRae S, Pagliai FA, Mohapatra NP, Gener A, Mahmou AS, Gunn JS, Lorca GL, Gonzalez CF. 2010. Inhibition of AcpA phosphatase activity with ascorbate attenuates Francisella tularensis intramacrophage survival. J. Biol. Chem. 285:5171-7. PMC2820744
Pubmed Abstract 

Quenee LE, Berube BJ, Segal J, Elli D, Ciletti NA, Anderson D, Schneewind O. 2010. Amino acid residues 196-225 of LcrV represent a plague protective epitope. Vaccine 28:1870-1876. PMC2822060
Pubmed Abstract 

Carlson PE, Dixon SD, Janes BK, Carr KA, Nusca TD, Anderson EC, Keene SE, Sherman DH, Hanna PC. 2010. Genetic analysis of petrobactin transport in Bacillus anthracis. Mol. Microbiol. 75:900-9. PMC2917102
Pubmed Abstract 

Ragle BE, Karginov VA, Bubeck Wardenburg J. 2010. Prevention and treatment of Staphylococcus aureus pneumonia with a beta-cyclodextrin derivative. Antimicrob. Agents Chemother. 54:298-304. PMC2798498
Pubmed Abstract 

Lin G, Tepp WH, Pier CL, Jacobson MJ, Johnson EA. 2010. Expression of the Clostridium botulinum A2 neurotoxin gene cluster proteins and characterization of the A2 complex. Appl. Environ. Microbiol. 76:40-7. PMC2798633
Pubmed Abstract 

Durward MA, Harms J, Magnani DM, Eskra L, Splitter GA. 2010. Discordant Brucella melitensis antigens yield cognate CD8+ T cells in vivo. Infect. Immun. 78:168-76. PMC2798188
Pubmed Abstract 

Wiebe MS, Nichols RJ, Molitor TP, Lindgren JK, Traktman P. 2010. Mice deficient in the serine/threonine protein kinase VRK1 are infertile due to a progressive loss of spermatogonia. Biol. Reprod. 82:182-93. PMC2802121
Pubmed Abstract 

Blaylock B, Berube BJ, Schneewind O. 2010. YopR impacts type III needle polymerization in Yersinia species. Mol. Microbiol. 75:221-9. PMC2839503
Pubmed Abstract 

Bradshaw M, Marshall KM, Heap JT, Tepp WH, Minton NP, Johnson EA. 2010. Construction of a nontoxigenic Clostridium botulinum strain for food challenge studies. Appl. Environ. Microbiol. 76:387-93. PMC2805223
Pubmed Abstract 

Kern J, Schneewind O. 2010. BslA, the S-layer adhesin of B. anthracis, is a virulence factor for anthrax pathogenesis. Mol. Microbiol. 75:324-32. PMC2828814
Pubmed Abstract 

Schlievert PM, Strandberg KL, Lin YC, Peterson ML, Leung DY. 2010. Secreted virulence factor comparison between methicillin-resistant and methicillin-sensitive Staphylococcus aureus, and its relevance to atopic dermatitis. J. Allergy Clin. Immunol. 125:39-49. PMC2814367
Pubmed Abstract 

Hutson CL, Abel JA, Carroll DS, Olson VA, Braden ZH, Hughes CM, Dillon M, Hopkins C, Karem KL, Damon IK, Osorio JE. 2010. Comparison of West African and Congo Basin monkeypox viruses in BALB/c and C57BL/6 mice. PLoS ONE 5:e8912. PMC2811726
Pubmed Abstract 

Henkel JS, Baldwin MR, Barbieri JT. 2010. Toxins from bacteria. EXS 100:1-29. NIHMS244650
Pubmed Abstract 

Bielinska AU, Gerber M, Blanco LP, Makidon PE, Janczak KW, Beer M, Swanson B, Baker JR. 2010. Induction of Th17 cellular immunity with a novel nanoemulsion adjuvant. Crit. Rev. Immunol. 30:189-99. PMC2860868
Pubmed Abstract 

Marshall KM, Bradshaw M, Johnson EA. 2010. Conjugative botulinum neurotoxin-encoding plasmids in Clostridium botulinum. PLoS ONE 5:e11087. PMC2884020
Pubmed Abstract 

Past years

2010 |2009 | 2008 | 2007 | 2006 | 2005 | 2004 | 2003

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